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Name :homocysteine (Hcy)

Clinical Significance

Is also called homocysteine, an amino acid containing sulfonium, body can't synthesis, can only come from methionine catabolism. Hcy is independent risk factor for cardiovascular disease, risk increased with the concentration increased. As the Hcy concentration increased, a 1.87 -fold increased risk of stroke. - type 2 diabetes blood Hcy concentration higher than that of normal controls, and associated with a significant HbAlc fasting glucose and diabetes duration; Diabetes patients plasma Hcy levels rising every 5 mu mol/L, 3 times increased mortality in the next five years. Chronic kidney disease patients due to the removal of Hcy dysfunction, Hcy increases in blood increased mortality of atherosclerosis and cardiovascular disease. Enzyme dysfunction or vitamin deficiency can result in higher Hcy.


Performance

(1) analysis of high sensitivity,

(2) the wide linear range: 0.5 ~ 50 mu mol/L;

(3) between batch and batch of precision are 3.8% or less; Accuracy by % 3.2% or less;

(4) strong anti-interference ability: the jaundice, lipid turbidity, hemolysis and other special sample has good anti-interference ability;

(5) good correlation: compared with imported one reagent tongfang reagent of law, results are in good consistency, N = 50, the correlation coefficient R2 = 0.9989;

(6) stability: airtight dark 2-8 ℃ can be stable for 12 months.



Name :Retinol binding protein (RBP)

Clinical Significance

Is a kind of low molecular weight lipid carrier protein, is a Lipocalin protein family members. Serum retinol binding protein, forming complexes combine with thyroxine prealbumin and take vitamin A carrier system function. The compound can be stable specific operation combined with retinol and cells, and RBP is just retinol in plasma is carried, redundant RBP by glomerular filtration, absorbed by proximal convoluted tubules, glomerular filtration rate lower, higher RBP in the blood, so the urine RBP increased significance for early diagnosis, is a kind of evaluation of kidney disease, especially a good indicator of renal tubular damage. In addition, the diseases of the liver and gallbladder system, hyperparathyroidism, malabsorption syndrome can cause blood RBP decreased, rise in chronic kidney disease.



Performance

(1) analysis of high sensitivity,

(2) the wide linear range, 0.1 126 mg/L;

(3) between batch and batch of precision are 3.9% or less; Accuracy by % 3.5% or less;

(4) strong anti-interference ability: the jaundice, lipid turbidity, hemolysis and other special sample has good anti-interference ability;

(5) good correlation: compared with imported one reagent tongfang reagent of law, results are in good consistency, N = 50, the correlation coefficient R2 = 0.9957;

(6) stability: airtight dark 2-8 ℃ can be stable for 12 months.